HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyethylamine → (2S,4EZ)-4-(tert-butoxyimino)-N2-(2-methoxyethyl)-N1-(3-methoxyphenyl)-1,2-pyrrolidinedicarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyethylamine | HCID 8018 | — |
| Reactant | 3-Methoxyphenyl isocyanate | HCID 87843 | — |
| Reactant | (2S,4EZ)-1-(tertbutoxycarbonyl)-4-(tert-butoxyimino)-2-pyrrolidinecarboxylic acid | HCID 131725425 | — |
| Product | (2S,4EZ)-4-(tert-butoxyimino)-N2-(2-methoxyethyl)-N1-(3-methoxyphenyl)-1,2-pyrrolidinedicarboxamide | HCID 131725525 | — |
Reaction Steps
Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(tert-butoxyimino)-2-pyrrolidinecarboxylic acid, 1-isocyanato-3-methoxybenzene, and 2-methoxyethylamine the title compound was obtained in 76% purity by LC/MS. MS(ESI+): m/z=407.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07211601B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-406598b3388447d59f1ffcdc6139465e |
| Source note | uspto-grants-2007_05 |