HRID1349173

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7412

Benzoyl chloride

C7H5ClO

HCID8588

3-Amino-9-ethylcarbazole

C14H14N2

结构：CC(C)(C)OC(=O)N1CC(=Cc2ccccc2)C[C@H]1C(=O)O

HCID69250545

未命名化合物

PRODUCTS

生成物

结构：CCn1c2ccccc2c2cc(NC(=O)[C@@H]3CC(=Cc4ccccc4)CN3C(=O)c3ccccc3)ccc21

HCID69250412

未命名化合物

PROCEDURE

实验过程

Following the general method as outlined in Example 22, starting from (2S,4EZ)-4benzylidene-1-(tert-butoxycarbonyl)-2-pyrrolidinecarboxylic acid, benzoyl chloride, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 81% purity by LC/MS. MS(ESI+): m/z=500.4.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-620412dc83ff457582cd6ee25362e8ec
来源数据集: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07211601B2
来源说明: uspto-grants-2007_05

反应 SMILES

[CH:1](=[C:8]1[CH2:12][N:11]([C:13]([O:15]C(C)(C)C)=O)[C@H:10]([C:20]([OH:22])=O)[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(Cl)(=O)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1.[CH2:32]([N:34]1[C:46]2[CH:45]=[CH:44][C:43]([NH2:47])=[CH:42][C:41]=2[C:40]2[C:35]1=[CH:36][CH:37]=[CH:38][CH:39]=2)[CH3:33]>>[C:13]([N:11]1[CH2:12][C:8](=[CH:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH2:9][C@H:10]1[C:20]([NH:47][C:43]1[CH:44]=[CH:45][C:46]2[N:34]([CH2:32][CH3:33])[C:35]3[C:40]([C:41]=2[CH:42]=1)=[CH:39][CH:38]=[CH:37][CH:36]=3)=[O:22])(=[O:15])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1