Benzo-1,3-dioxole-5-methylamine → HCID 69251273, compound

HRID 1349203Notes

Reaction equation

HRID 1349203 reaction equation
C(OC([N:8]1[CH2:15][C:14](=[O:16])[CH2:13][C@H:9]1[C:10]([OH:12])=O)=O)(C)(C)C.[O:17]1[C:21]2[CH:22]=[CH:23][C:24]([CH2:26][NH2:27])=[CH:25][C:20]=2[O:19][CH2:18]1>>[O:17]1[C:21]2[CH:22]=[CH:23][C:24]([CH2:26][NH:27][C:10]([C@@H:9]3[CH2:13][C:14](=[O:16])[CH2:15][NH:8]3)=[O:12])=[CH:25][C:20]=2[O:19][CH2:18]1

Participants

3

Reactant 2

HCID 75799Benzo-1,3-dioxole-5-methylamineHCID 11593804(2S)-1-(tert-butoxycarbonyl)-4-oxopyrrolidine-2-carboxylic acid

Product 1

HCID 69251273HCID 69251273, compound

Procedure

Following the general method as outlined in Example 22, starting from 1-(tert-butoxycarbonyl)-4-oxoproline, and 1,3-benzodioxol-5-ylmethylamine the title compound was obtained in 71% purity by LC/MS. MS(ESI+): m/z=263.0.

Sources & evidence

ORD record
ord-e28c5f2d8f6e4435bae75106a01060b5
Source dataset
uspto-grants-2007_05
Patent number
US07211601B2

Reaction notes

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