Norfenefrine → (2S,4EZ)-N-[(2RS)-2 hydroxy-2-(3-hydroxyphenyl)ethyl]-4(methoxyimino)-1-[(2',6'-dimethyl[1,1'-biphenyl]-4-yl)carbonyl]-2-pyrrolidinecarboxamide

Beteiligte Stoffe

Reaktionsschritte

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid, 2′,6′-dimethyl[1,1′-biphenyl]-4-carboxylic acid, and 3-[(1RS)-2-amino-1-hydroxyethyl]phenol, the title compound was obtained in 87% purity by HPLC. MS(ESI+): m/z=502.

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