1-Bromohexan-2-one → 2-(1-Bromocyclopropyl)-4-ethylthiazole

HRID 1349355Notes

Reaction equation

HRID 1349355 reaction equation
[Br:1][C:2]1([C:5]2[S:6][CH:7]=[C:8]([CH2:10][CH2:11]CC)[N:9]=2)[CH2:4][CH2:3]1.BrCC(=O)CCCC>>[Br:1][C:2]1([C:5]2[S:6][CH:7]=[C:8]([CH2:10][CH3:11])[N:9]=2)[CH2:3][CH2:4]1

Participants

3

Reactant 2

HCID 124317331-Bromohexan-2-oneHCID 158378752-(1-Bromocyclopropyl)-4-butylthiazole

Product 1

HCID 158378722-(1-Bromocyclopropyl)-4-ethylthiazole

Procedure

2-(1-Bromocyclopropyl)-4-butylthiazole 20 from 1-bromo-2-hexanone at 100° C. and a reaction time of 2 minutes.

Workup

  1. customat 100° C.
  2. customa reaction time of 2 minutes

Sources & evidence

ORD record
ord-a0243c12981d45cf9ccd6b28aaee13b3
Source dataset
uspto-grants-2007_05
Patent number
US07211680B2

Reaction notes

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