反应详情

To a solution of 3-benzyloxy-1-(2,2-dimethoxyethyl)-5-isopropenyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid 3-chlorobenzylamide (60 mg) in methanol (1 ml) was added 5% palladium-carbon (20 mg) and the mixture was stirred under an atmospheric pressure of hydrogen for 16 hr. A solid was filtered off and the filtrate was concentrated to give 1-(2,2-dimethoxyethyl)-3-hydroxy-5-isopropyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid 3-chlorobenzylamide (43 mg).

1. filtrationA solid was filtered off
2. concentrationthe filtrate was concentrated