2-Furancarbonyl chloride → HCID 86591999, compound

HRID 1349522Notes

Reaction equation

HRID 1349522 reaction equation
[CH2:1]([C@H:3]1[CH2:12][C@@H:11]([N:13]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:14](=[O:16])[CH3:15])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]1[C:23]([C:25]1[S:29][C:28]([C:30]2[CH:35]=[N:34][CH:33]=[CH:32][N:31]=2)=[N:27][C:26]=1[CH3:36])=[O:24])C.O1C=CC=C1C(Cl)=O>>[CH3:1][C@H:3]1[CH2:12][C@@H:11]([N:13]([C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)[C:14](=[O:16])[CH3:15])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]1[C:23]([C:25]1[S:29][C:28]([C:30]2[CH:35]=[N:34][CH:33]=[CH:32][N:31]=2)=[N:27][C:26]=1[CH3:36])=[O:24]

Participants

3

Reactant 2

HCID 682422-Furancarbonyl chlorideHCID 86592000HCID 86592000, compound

Product 1

HCID 86591999HCID 86591999, compound

Procedure

(±)-Cis-N-[2-ethyl-1-(4-methyl-2-pyrazin-2-yl-thiazole-5-carbonyl)-1,2,3,4-tetrahydro-quinolin-4-yl]-N-phenyl-acetamide was made following general procedure A, substituting 4-methyl-2-(2-pyrazinyl)-1,3-thiazole-5-carbonyl chloride for 2-furoyl chloride.

Sources & evidence

ORD record
ord-bfb218ac50104a22b2be18d107bf2209
Source dataset
uspto-grants-2007_05
Patent number
US07211672B2

Reaction notes

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