4-(Dimethylamino)benzoyl chloride → HCID 21092881, compound

HRID 1349540Notes

Reaction equation

HRID 1349540 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]([C@H:12]2[C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[N:15]([C:22](=[O:31])[C:23]3[CH:28]=[CH:27][CH:26]=[C:25]([O:29][CH3:30])[CH:24]=3)[C@@H:14]([CH3:32])[CH2:13]2)[C:9](=[O:11])[CH3:10])=[CH:4][CH:3]=1.CN(C)C1C=CC(C(Cl)=O)=CC=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]([CH:12]2[C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[N:15]([C:22](=[O:31])[C:23]3[CH:28]=[CH:27][CH:26]=[C:25]([O:29][CH3:30])[CH:24]=3)[CH:14]([CH3:32])[CH2:13]2)[C:9](=[O:11])[CH3:10])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 44007824-(Dimethylamino)benzoyl chlorideHCID 10003832HCID 10003832, compound

Product 1

HCID 21092881HCID 21092881, compound

Procedure

(±)-Cis-N-(4-chloro-phenyl)-N-[1-(3-methoxy-benzoyl)-2-methyl-1,2,3,4-tetrahydro-quinolin-4-yl]-acetamide was made following general procedure B, substituting 3-methoxybenzoyl chloride for 4-dimethylaminobenzoyl chloride.

Sources & evidence

ORD record
ord-6e8b594df2eb4ea0818fb201b905ed7c
Source dataset
uspto-grants-2007_05
Patent number
US07211672B2

Reaction notes

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