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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1349547Generated: October 30, 2026

Aniline → HCID 10457089, compound

https://huagongshe.com/reaction/1349547

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnilineHCID 6115—
Reactantp-Anisoyl chlorideHCID 7477—
Reactant4-(Dimethylamino)benzoyl chlorideHCID 4400782—
ReactantHCID 86592032HCID 86592032—
ProductHCID 10457089HCID 10457089—

Reaction Steps

(±)-Cis-N-(4-chloro-phenyl)-N-[1-(4-methoxy-benzoyl)-2,5-dimethyl-1,2,3,4-tetrahydro-quinolin-4-yl]-acetamide was made following general procedure B, substituting 3-toluidine for aniline and 4-methoxybenzoyl chloride for 4-dimethylaminobenzoyl chloride. The reaction was non-selective and also (±)-cis-N-(4-chloro-phenyl)-N-[1-(4-methoxy-benzoyl)-2,7-dimethyl-1,2,3,4-tetrahydro-quinolin-4-yl]-acetamide was obtained in a 1:1 mixture with the product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07211672B2
Source datasetuspto-grants-2007_05
ORD IDord-709b8c54b0cd4fb5a0229a968e9f2685
Source noteuspto-grants-2007_05