Tributyltin azide → HCID 22480179, compound

HRID 1349663Notes

Reaction equation

HRID 1349663 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[C:15]3[C:10](=[CH:11][CH:12]=[C:13]([C:16]#[N:17])[CH:14]=3)[NH:9][N:8]=2)[CH:2]=1.[N:18]([Sn](CCCC)(CCCC)CCCC)=[N+:19]=[N-:20]>C1(C)C=CC=CC=1>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[C:15]3[C:10](=[CH:11][CH:12]=[C:13]([C:16]4[N:18]=[N:19][NH:20][N:17]=4)[CH:14]=3)[NH:9][N:8]=2)[CH:2]=1

Participants

4

Reactant 2

HCID 4984872Tributyltin azideHCID 22479720HCID 22479720, compound

Product 1

HCID 22480179HCID 22480179, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

The title compound was prepared from 3-(3-pyridyl)-1H-indazole-5-carbonitrile (0.068 g, 0.031 mmol), azidotributyl tin (0.116 g, 0.096 mL, 0.32 mmol) in toluene (10 mL). The product was isolated using the procedure described for Example 161 (0.009 g, 0.04 mmol, 12.5% yield): 1H NMR (DMSO-d6) δ 14.0 (br s, 1H), 9.2 (d, 1H), 8.8 (s, 1H), 8.7 (d, 1H), 8.5 (d, 1H), 7.83–7.78 (m, 2H), 7.76–7.64 (m, 1H); ES-MS (m/z) 264 [M+1]+.

Workup

  1. customThe product was isolated

Sources & evidence

ORD record
ord-699ad5a4499147b89af070219cdb1fb9
Source dataset
uspto-grants-2007_05
Patent number
US07211594B2

Reaction notes

Loading…