HCID 21093746, compound → 8-{1-[2-(7-Chloro-2-methylquinolin-5-yloxy)ethyl]piperidin-4-ylmethyl}-4H-benzo[1,4]oxazin-3-one

HRID 1349962Notes

Reaction equation

HRID 1349962 reaction equation
[NH:1]1[CH2:6][CH2:5][CH:4]([CH2:7][C:8]2[C:17]3[O:16][CH2:15][C:14](=[O:18])[NH:13][C:12]=3[CH:11]=[CH:10][CH:9]=2)[CH2:3][CH2:2]1.Br[CH2:20][CH2:21][O:22][C:23]1[CH:32]=[C:31]([Cl:33])[CH:30]=[C:29]2[C:24]=1[CH:25]=[CH:26][C:27]([CH3:34])=[N:28]2>>[Cl:33][C:31]1[CH:30]=[C:29]2[C:24]([CH:25]=[CH:26][C:27]([CH3:34])=[N:28]2)=[C:23]([O:22][CH2:21][CH2:20][N:1]2[CH2:6][CH2:5][CH:4]([CH2:7][C:8]3[C:17]4[O:16][CH2:15][C:14](=[O:18])[NH:13][C:12]=4[CH:11]=[CH:10][CH:9]=3)[CH2:3][CH2:2]2)[CH:32]=1

Participants

3

Reactant 2

HCID 21093746HCID 21093746, compoundHCID 210937508-piperidin-4-ylmethyl-4H-benzo[1,4]oxazin-3-one

Product 1

HCID 103107468-{1-[2-(7-Chloro-2-methylquinolin-5-yloxy)ethyl]piperidin-4-ylmethyl}-4H-benzo[1,4]oxazin-3-one

Procedure

The title compound was prepared from 8-(piperidin-4-ylmethyl)-4H-benzo[1,4]oxazin-3-one and 5-(2-bromoethoxy)-7-chloro-2-methylquinoline in a similar manner to Example 1.

Sources & evidence

ORD record
ord-a24b2d5c449e4279b29a829ee29d7a53
Source dataset
uspto-grants-2007_05
Patent number
US07214674B2

Reaction notes

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