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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1349966Generated: November 1, 2026

4-methyl-8-(piperidin-4-ylmethyl)4H-benzo[1,4]oxazin-3-one → 8-{1-[2-(7-Chloro-2-methylquinolin-5-yloxy)ethyl]piperidin-4-ylmethyl}-4-methyl-4H-benzo[1,4]oxazin-3-one

https://huagongshe.com/reaction/1349966

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-methyl-8-(piperidin-4-ylmethyl)4H-benzo[1,4]oxazin-3-oneHCID 21093745—
ReactantHCID 21093746HCID 21093746—
Product8-{1-[2-(7-Chloro-2-methylquinolin-5-yloxy)ethyl]piperidin-4-ylmethyl}-4-methyl-4H-benzo[1,4]oxazin-3-oneHCID 10152045—

Reaction Steps

The title compound was prepared from 4-methyl-8-(piperidin-4-ylmethyl)-4H-benzo[1,4]oxazin-3-one and 5-(2-bromoethoxy)-7-chloro-2-methylquinoline in a similar manner to Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07214674B2
Source datasetuspto-grants-2007_05
ORD IDord-57fe6158fa9848b8b74761d4561e4c10
Source noteuspto-grants-2007_05