2-(2-Chlorophenyl)ethylamine → HCID 10194045, compound

HRID 1350051Notes

Reaction equation

HRID 1350051 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][C:8]([N:11]2[C:16](=[O:17])[NH:15][C:14](=[O:18])[CH:13]=[N:12]2)=[CH:7][C:3]=1[C:4]([OH:6])=O.[Cl:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[CH2:26][CH2:27][NH2:28]>>[Cl:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[CH2:26][CH2:27][NH:28][C:4](=[O:6])[C:3]1[CH:7]=[C:8]([N:11]2[C:16](=[O:17])[NH:15][C:14](=[O:18])[CH:13]=[N:12]2)[CH:9]=[CH:10][C:2]=1[CH3:1]

Participants

3

Reactant 2

HCID 831172-(2-Chlorophenyl)ethylamineHCID 222674555-(3,5-Dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)-2-methylbenzoic acid

Product 1

HCID 10194045HCID 10194045, compound

Procedure

The title compound was prepared using the method outlined in Example 48, coupling 2-methyl-5-(3,5-dioxo-4,5-dihydro-3H-[1,2,4]triazin-2-yl)-benzoic acid with 2-(ortho-chlorophenyl)ethylamine. The product was a colorless oil. MS (ES+) 385.2; (ES−) 383.2; LC retention time=2.1 min (using the LC/MS and method outlined for the examples in Table 1).

Sources & evidence

ORD record
ord-3fe19b4c9a9d45cba63a1d5939fbeb54
Source dataset
uspto-grants-2007_05
Patent number
US07214677B2

Reaction notes

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