Ethyl formate → HCID 21094280, compound

Participants

Reaction Steps

The amine obtained in Step B, in the form of a base (6.4 g; 27 mmol), is dissolved in 60 ml of ethyl formate. The reaction mixture is heated at reflux for 6 hours with stirring and then evaporated under reduced pressure. The residue obtained is taken up in ether. The organic phase is then washed in succession with acidic water (1N HCl), water, and a 10% hydrogen carbonate solution, subsequently dried over magnesium sulphate, filtered and evaporated under reduced pressure to yield the title product in the form of a yellow oil.

Provenance & Evidence