Water → HCID 21094318, compound

Participants

Reaction Conditions

Reaction Steps

The compound obtained in Step G (10.5 g; 36 mmol) is dissolved in 150 ml of dichloromethane and then triethylamine (8.5 ml) is added. The solution is cooled to 0° C. and methanesulphonyl choride (4.8 ml; 62 mmol) is added dropwise. The reaction mixture is stirred at ambient temperature for 2 hours and then poured into 150 ml of water. The solution is extracted with dichloromethane, dried over magnesium sulphate, filtered and evaporated under reduced pressure. The title compound is purified by chromatography on silica gel.

Provenance & Evidence