反应详情

温度

180 °C

Oxane-4,4-dicarboxylic acid was taken in a round bottom flask fitted with a reflux condenser and was gradually heated to 180° C. When evolution of carbon dioxide decreased, the reaction was allowed to cool to room temperature. The monoacid thus obtained was purified by distillation (160–165° C. at 22 mm Hg) to yield oxane-4-carboxylic acid (16.1 g, 71.8% yield).

1. customfitted with a reflux condenser
2. temperatureto cool to room temperature
3. customThe monoacid thus obtained
4. distillationwas purified by distillation (160–165° C. at 22 mm Hg)