Ethyl benzoylformate → HCID 69507578, compound

HRID 1350180Notes

Reaction equation

HRID 1350180 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][C:2]1=[O:10].[C:11]1([C:17](=O)[C:18]([O:20]CC)=[O:19])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[O:10]=[C:2]1[C:3](=[C:17]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:18]([OH:20])=[O:19])[C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[NH:1]1

Participants

3

Reactant 2

HCID 15349Ethyl benzoylformateHCID 321710Oxindole

Product 1

HCID 69507578HCID 69507578, compoundYield 25.1%

Procedure

Oxindole (390 mg, 3mmol) was condensed with ethyl phenylglyoxylate (540 mg) using method A to give 200 mg (25%) of the title compound as a yellow solid.

Sources & evidence

ORD record
ord-1e88cfeedc2049ccaa816536e40be060
Source dataset
uspto-grants-2007_05
Patent number
US07214700B2

Reaction notes

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