3-Fluoroaniline → HCID 69507416, compound

HRID 1350182Notes

Reaction equation

[CH3:1][C:2]1[CH:6]=[C:5]([CH3:7])[NH:4][C:3]=1[C:8](=[C:12]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[NH:14][C:13]1=[O:21])[C:9]([OH:11])=O.[F:22][C:23]1[CH:24]=[C:25]([CH:27]=[CH:28][CH:29]=1)[NH2:26]>>[CH3:1][C:2]1[CH:6]=[C:5]([CH3:7])[NH:4][C:3]=1[C:8](=[C:12]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[NH:14][C:13]1=[O:21])[C:9]([NH:26][C:25]1[CH:27]=[CH:28][CH:29]=[C:23]([F:22])[CH:24]=1)=[O:11]

Participants

Reactant 2

HCID 97423-Fluoroaniline

HCID 69453471HCID 69453471, compound

Product 1

HCID 69507416HCID 69507416, compoundYield 21.1%

Procedure

(3,5-Dimethyl-1H-pyrrol-2-yl)-(2-oxo-1,2-dihydroindol-3-ylidene)-acetic acid (90 mg) was reacted with 3-fluoroaniline (35 mg) using method B to give 25 mg (21%) of the title compound.

Sources & evidence

ORD record: ord-bf866742b0db4c26a0214cfce8917265
Source dataset: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07214700B2

Reaction notes

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