4-Amino-2-[(diethylamino)methyl]phenol dihydrochloride → HCID 69507261, compound

HRID 1350186Notes

Reaction equation

HRID 1350186 reaction equation
[CH3:1][C:2]1[CH:6]=[C:5]([CH3:7])[NH:4][C:3]=1[C:8](=[C:12]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[NH:14][C:13]1=[O:21])[C:9](O)=[O:10].Cl.Cl.[NH2:24][C:25]1[CH:26]=[C:27]([CH2:32][N:33]([CH2:36][CH3:37])[CH2:34][CH3:35])[C:28]([OH:31])=[CH:29][CH:30]=1>>[CH2:34]([N:33]([CH2:32][C:27]1[CH:26]=[C:25]([NH:24][C:9](=[O:10])[C:8]([C:3]2[NH:4][C:5]([CH3:7])=[CH:6][C:2]=2[CH3:1])=[C:12]2[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[NH:14][C:13]2=[O:21])[CH:30]=[CH:29][C:28]=1[OH:31])[CH2:36][CH3:37])[CH3:35]

Participants

3

Reactant 2

HCID 27238784-Amino-2-[(diethylamino)methyl]phenol dihydrochlorideHCID 69453471HCID 69453471, compound

Product 1

HCID 69507261HCID 69507261, compoundYield 17.1%

Procedure

(3,5-Dimethyl-1H-pyrrol-2-yl)-(2-oxo-1,2-dihydroindol-3-ylidene)-acetic acid (90 mg) was reacted with 4-amino-alpha-diethylamino-o-cresol dihydrochloride (110 mg) using method B to give 25 mg (17%) of the title compound.

Sources & evidence

ORD record
ord-a7c765c9c3fa4c568cec4b7f59b14b6a
Source dataset
uspto-grants-2007_05
Patent number
US07214700B2

Reaction notes

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