Methyl phenylglyoxalate → HCID 69507184, compound

HRID 1350189Notes

Reaction equation

HRID 1350189 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[CH2:5]2.[C:12]1([C:18](=O)[C:19]([O:21]C)=[O:20])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2=[C:18]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:19]([OH:21])=[O:20]

Participants

3

Reactant 2

HCID 84835Methyl phenylglyoxalateHCID 6111935-Bromo-2-oxindole

Product 1

HCID 69507184HCID 69507184, compoundYield 45.2%

Procedure

5-Bromooxindole (640 mg) was reacted with methyl phenylglyoxylate (540 mg) using method A to give 470 mg (45%) of the title compound.

Sources & evidence

ORD record
ord-8824b96fe4504fe892ac5c887915a07c
Source dataset
uspto-grants-2007_05
Patent number
US07214700B2

Reaction notes

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