HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 5-(4-nitrophenoxy)pyridine-3-carboxylate → 5-(4-Aminophenoxy)nicotinic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 5-(4-nitrophenoxy)pyridine-3-carboxylate | HCID 22040734 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-(4-Aminophenoxy)nicotinic acid methyl ester | HCID 22040606 | — |
Reaction Steps
The mixture containing methyl-5-(4-nitrophenoxy)pyridine-3-carboxylate in methanol with catalytic amount of 10% Pd/C was hydrogenated to yield methyl5-[4-aminophenoxy]pyridine-3-carboxylate. MS: MH+=244.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07728010B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-4b4b851f6c574ce7b9e369a2ecc32f20 |
| Source note | uspto-grants-2010_06 |