HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → tert-butyl(3R)-3-(3-{[(3-chloropropyl)sulfonyl]amino}-1,2,4-oxadiazol-5-yl)-6-cyclohexylhexanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 3-Chloropropanesulphonyl chloride | HCID 15410 | — |
| Reactant | tert-butyl(3R)-3-[3-(aminomethyl)-1,2,4-oxadiazol-5-yl]-6-cyclohexylhexanoate | HCID 16747946 | — |
| Product | tert-butyl(3R)-3-(3-{[(3-chloropropyl)sulfonyl]amino}-1,2,4-oxadiazol-5-yl)-6-cyclohexylhexanoate | HCID 69432927 | — |
Reaction Steps
Method as for preparation 10 using tert-butyl(3R)-3-[3-(aminomethyl)-1,2,4-oxadiazol-5-yl]-6-cyclohexylhexanoate (preparation 18) (200 mg, 0.57 mmol) and 3-chloropropanesulphonyl chloride (83 μl, 0.68 mmol) as starting materials and pyridine as the base.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07214694B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-73bd99f27a8d4748bd8e2c834f94fa2e |
| Source note | uspto-grants-2007_05 |