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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1350218Generated: November 1, 2026

Cyclopropanecarbonyl chloride → HCID 60077593, compound

https://huagongshe.com/reaction/1350218

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanecarbonyl chlorideHCID 77637—
Reactanttert-butyl(3R)-3-[3-(aminomethyl)-1,2,4-oxadiazol-5-yl]-6-cyclohexylhexanoateHCID 16747946—
ProductHCID 60077593HCID 60077593107.5%

Reaction Steps

Method as for preparation 50 using tert-butyl(3R)-3-[3-(aminomethyl)-1,2,4-oxadiazol-5-yl]-6-cyclohexylhexanoate (preparation 18) (204 mg, 0.57 mmol) and cyclopropane carboxylic acid chloride (62 μl, 0.68 mmol) as starting materials to afford the title compound as a colourless oil (257 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07214694B2
Source datasetuspto-grants-2007_05
ORD IDord-0cb5f944ac7f43519691ba56852c195b
Source noteuspto-grants-2007_05