N,N-Dimethylglycine → HCID 60077666, compound

HRID 1350220Notes

Reaction equation

HRID 1350220 reaction equation
[NH2:1][CH2:2][C:3]1[N:7]=[C:6]([C@H:8]([CH2:17][CH2:18][CH2:19][CH:20]2[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]2)[CH2:9][C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])[O:5][N:4]=1.[CH3:26][N:27]([CH3:32])[CH2:28][C:29](O)=[O:30]>>[CH:20]1([CH2:19][CH2:18][CH2:17][C@@H:8]([C:6]2[O:5][N:4]=[C:3]([CH2:2][NH:1][C:29](=[O:30])[CH2:28][N:27]([CH3:32])[CH3:26])[N:7]=2)[CH2:9][C:10]([O:12][C:13]([CH3:15])([CH3:16])[CH3:14])=[O:11])[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]1

Participants

3

Reactant 2

HCID 673N,N-DimethylglycineHCID 16747946tert-butyl(3R)-3-[3-(aminomethyl)-1,2,4-oxadiazol-5-yl]-6-cyclohexylhexanoate

Product 1

HCID 60077666HCID 60077666, compound

Procedure

Method as for preparation 56 using tert-butyl(3R)-3-[3-(aminomethyl)-1,2,4-oxadiazol-5-yl]-6-cyclohexylhexanoate (preparation 18) (206 mg, 0.57 mmol) and N,N-dimethylglycine (65 mg, 0.63 mmol) as starting materials.

Sources & evidence

ORD record
ord-8849684dd7cf47249bedf836bf3c1028
Source dataset
uspto-grants-2007_05
Patent number
US07214694B2

Reaction notes

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