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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1350227Generated: November 1, 2026

Propylamine → tert-butyl(3R)-6-cyclohexyl-3-{3-[(propylamino)methyl]-1,2,4-oxadiazol-5-yl}hexanoate

https://huagongshe.com/reaction/1350227

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropylamineHCID 7852—
Reactanttert-Butyl (3R)-6-cyclohexyl-3-[3-({[(4-methylphenyl)sulfonyl]oxy}methyl)1,2,4-oxadiazol-5-yl]hexanoateHCID 16747945—
Producttert-butyl(3R)-6-cyclohexyl-3-{3-[(propylamino)methyl]-1,2,4-oxadiazol-5-yl}hexanoateHCID 60077650—

Reaction Steps

Method as for preparation 5 using tert-butyl(3R)-6-cyclohexyl-3-[3-({[(4-methylphenyl)sulfonyl]oxy}methyl)-1,2,4-oxadiazol-5-yl]hexanoate (preparation 177) (500 mg, 1.00 mmol) and propylamine (175 mg, 3.00 mmol) as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07214694B2
Source datasetuspto-grants-2007_05
ORD IDord-c8299230f9bb4a57a3a7435bf41f24bc
Source noteuspto-grants-2007_05