2-[2-(Tert-butoxy)-2-oxoethyl]-5-cyclohexylpentanoic acid → HCID 60077623, compound

HRID 1350256Notes

Reaction equation

HRID 1350256 reaction equation
[C:1]([O:5][C:6](=[O:21])[CH2:7][CH:8]([CH2:12][CH2:13][CH2:14][CH:15]1[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1)[C:9]([OH:11])=O)([CH3:4])([CH3:3])[CH3:2].O[NH:23][C:24](=[NH:31])[CH2:25][N:26]1[CH:30]=[N:29][CH:28]=[N:27]1>>[CH:15]1([CH2:14][CH2:13][CH2:12][C@@H:8]([C:9]2[O:11][N:31]=[C:24]([CH2:25][N:26]3[CH:30]=[N:29][CH:28]=[N:27]3)[N:23]=2)[CH2:7][C:6]([O:5][C:1]([CH3:2])([CH3:3])[CH3:4])=[O:21])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1

Participants

3

Reactant 2

HCID 213050372-[2-(Tert-butoxy)-2-oxoethyl]-5-cyclohexylpentanoic acidHCID 178511319HCID 178511319, compound

Product 1

HCID 60077623HCID 60077623, compound

Procedure

Method as for preparation 2 and 3 combined using 2-[2-(tert-butoxy)-2-oxoethyl]-5-cyclohexylpentanoic acid (preparation 168) (2.98 g, 10 mmol) and N-hydroxy-2-(1H-1,2,4-triazol-1-yl)ethanimidamide (preparation 148) (1.01 g, 10 mmol) as starting materials.

Workup

  1. customMethod as for preparation 2 and 3

Sources & evidence

ORD record
ord-ee862feefe784d36aee4511725dc6d4f
Source dataset
uspto-grants-2007_05
Patent number
US07214694B2

Reaction notes

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