Sodium ion → (2-Fluoro-6-hydroxymethyl-4-trifluoromethyl-phenyl)-methanol

HRID 135043Notes

Reaction equation

HRID 135043 reaction equation
[BH4-:36].[F:1][c:2]1[cH:3][c:4]([C:12]([N:13]([CH:14]([CH3:15])[CH3:16])[CH:17]([CH3:18])[CH3:19])=[O:20])[cH:5][c:6]([C:7]([F:8])([F:9])[F:10])[cH:11]1.[F:21][c:22]1[c:23]2[c:27]([cH:28][c:29]([C:31]([F:32])([F:33])[F:34])[cH:30]1)[C:26](=[O:35])[O:25][CH2:24]2.[Na+:37]>>[F:21][c:22]1[c:23]([CH2:24][OH:25])[c:27]([CH2:26][OH:35])[cH:28][c:29]([C:31]([F:32])([F:33])[F:34])[cH:30]1

Participants

5

Reactant 4

HCID 923Sodium ionHCID 28123BorohydrideHCID 442031433-Fluoro-N,N-diisopropyl-5-trifluoromethyl-benzamideHCID 577532554-Fluoro-6-trifluoromethyl-3H-isobenzofuran-1-one

Product 1

HCID 57753663(2-Fluoro-6-hydroxymethyl-4-trifluoromethyl-phenyl)-methanol

Sources & evidence

ORD record
ord-3dfe35759d824f65b3f4664f6782b8e8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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