HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Ethynylpyridine → 4-Fluoro-3-(4-pyridin-3-yl-[1,2,3]triazol-1-yl)-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Ethynylpyridine | HCID 186003 | — |
| Reactant | 3-[4-(6-Chloro-pyridin-3-yl)-1,2,3-triazol-1-yl]-4-methyl-benzoic acid | HCID 21097292 | — |
| Reactant | 3-Azido-4-fluorobenzoic acid | HCID 58784911 | — |
| Product | 4-Fluoro-3-(4-pyridin-3-yl-[1,2,3]triazol-1-yl)-benzoic acid | HCID 21097321 | — |
Reaction Steps
4-Fluoro-3-(4-pyridin-3-yl-[1,2,3]triazol-1-yl)-benzoic acid was prepared from 3-azido-4-fluoro benzoic acid (U.S. Ser. No. 04/102,492) and 3-ethynyl pyridine (Aldrich) in the same manner as 3-[4-(6-chloro-pyridin-3-yl)-1,2,3-triazol-1-yl]-4-methyl-benzoic acid (Example 1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07214802B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-f7ec658b8d2e493681fb81e4b1762258 |
| Source note | uspto-grants-2007_05 |