HRID1350661

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21097331

未命名化合物

HCID21097366

未命名化合物

PRODUCTS

生成物

结构：COc1c(CN(C)CCN(C)C)cc(C(C)(C)C)cc1NC(=O)c1ccc(C)c(-n2cc(-c3cccnc3)nn2)c1

HCID21097109

未命名化合物

PROCEDURE

实验过程

Example 10 was prepared by coupling 4-methyl-3-(4-pyridin-3-yl-[1,2,3]triazol-1-yl)-benzoic acid with N-(3-amino-5-tert-butyl-2-methoxy-benzyl)-N,N′,N′-trimethyl-ethane-1,2-diamine (see U.S. provisional application 60/526,569) in the same manner as Example 1. ESI MS m/z 554 [C32H41N7O2−H]−.

WORKUP

后处理

customExample 10 was prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a8f48eb563b1484e9a2ae3d1ca9f2c2e
来源数据集: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07214802B2
来源说明: uspto-grants-2007_05

反应 SMILES

[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[CH:4][C:3]=1[N:11]1[CH:15]=[C:14]([C:16]2[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=2)[N:13]=[N:12]1.[NH2:22][C:23]1[C:24]([O:41][CH3:42])=[C:25]([CH:34]=[C:35]([C:37]([CH3:40])([CH3:39])[CH3:38])[CH:36]=1)[CH2:26][N:27]([CH3:33])[CH2:28][CH2:29][N:30]([CH3:32])[CH3:31]>>[C:37]([C:35]1[CH:34]=[C:25]([CH2:26][N:27]([CH2:28][CH2:29][N:30]([CH3:31])[CH3:32])[CH3:33])[C:24]([O:41][CH3:42])=[C:23]([NH:22][C:6](=[O:8])[C:5]2[CH:9]=[CH:10][C:2]([CH3:1])=[C:3]([N:11]3[CH:15]=[C:14]([C:16]4[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=4)[N:13]=[N:12]3)[CH:4]=2)[CH:36]=1)([CH3:40])([CH3:38])[CH3:39]