3-Ethynylpyridine → HCID 21097180, compound

HRID 1350673Notes

Reaction equation

[N:1]([C:4]1[CH:5]=[C:6]([CH:27]=[CH:28][CH:29]=1)[C:7]([NH:9][C:10]1[CH:15]=[C:14]([C:16]([CH3:19])([CH3:18])[CH3:17])[CH:13]=[C:12]([NH:20][S:21]([CH3:24])(=[O:23])=[O:22])[C:11]=1[O:25][CH3:26])=[O:8])=[N+:2]=[N-:3].[C:30]([C:32]1[CH:33]=[N:34][CH:35]=[CH:36][CH:37]=1)#[CH:31]>>[C:16]([C:14]1[CH:13]=[C:12]([NH:20][S:21]([CH3:24])(=[O:22])=[O:23])[C:11]([O:25][CH3:26])=[C:10]([NH:9][C:7](=[O:8])[C:6]2[CH:27]=[CH:28][CH:29]=[C:4]([N:1]3[CH:31]=[C:30]([C:32]4[CH:33]=[N:34][CH:35]=[CH:36][CH:37]=4)[N:3]=[N:2]3)[CH:5]=2)[CH:15]=1)([CH3:17])([CH3:18])[CH3:19]

Participants

Reactant 2

HCID 1860033-Ethynylpyridine

HCID 21097303HCID 21097303, compound

Product 1

HCID 21097180HCID 21097180, compound

Procedure

Example 16 was prepared from 3-azido-N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-benzamide and 3-ethynyl pyridine in the same manner as Example 15. ESI MS m/z 521 [C26H28N6O4S+H]+.

Sources & evidence

ORD record: ord-d5250511807644668465836accdc2071
Source dataset: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07214802B2

Reaction notes

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