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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1350675Generated: November 2, 2026

5-Ethynyl-1-methyl-1H-imidazole → N-(5-tert-Butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-3-[4-(3-methyl-3H-imidazol-4-yl)-[1,2,3]triazol-1-yl]-benzamide

https://huagongshe.com/reaction/1350675

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Ethynyl-1-methyl-1H-imidazoleHCID 3333106—
Reactant3-azido-N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-benzamideHCID 21079202—
ProductN-(5-tert-Butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-3-[4-(3-methyl-3H-imidazol-4-yl)-[1,2,3]triazol-1-yl]-benzamideHCID 21097200—

Reaction Steps

Example 18 was prepared from 3-azido-N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-benzamide and 5-ethynyl-1-methyl-1H-imidazole (Aldrich) in the same manner as Example 15. ESI MS m/z 538 [C26H31N7O4S+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07214802B2
Source datasetuspto-grants-2007_05
ORD IDord-94824ef92f8a48febe455c91f637b6ab
Source noteuspto-grants-2007_05