HRID1350692

反应详情

EQUATION

反应方程式

REACTANTS

反应物

反应SMILES：COc1c(NC(=O)c2ccc(C)c(N=[N+]=[N-])c2)cc(C(C)(C)C)cc1NS(C)(=O)=O

HCID21079202

未命名化合物

HCID21097347

未命名化合物

PRODUCTS

产物

反应SMILES：COc1c(NC(=O)c2ccc(C)c(-n3cc(-c4cnc(SC)n4C)nn3)c2)cc(C(C)(C)C)cc1NS(C)(=O)=O

HCID21097194

未命名化合物

PROCEDURE

实验过程

Example 25 was prepared from 3-azido-N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-benzamide and 5-ethynyl-1-methyl-2-methylsulfanyl-1H-imidazole in the same manner as Example 15. ESI MS m/z 584 [C27H33N7O4S+H]+.

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-27bb456d4794433085418a1d23e2041c
来源数据集: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US07214802B2
来源说明: uspto-grants-2007_05

反应SMILES

[N:1]([C:4]1[CH:5]=[C:6]([CH:27]=[CH:28][C:29]=1[CH3:30])[C:7]([NH:9][C:10]1[CH:15]=[C:14]([C:16]([CH3:19])([CH3:18])[CH3:17])[CH:13]=[C:12]([NH:20][S:21]([CH3:24])(=[O:23])=[O:22])[C:11]=1[O:25][CH3:26])=[O:8])=[N+:2]=[N-:3].[C:31]([C:33]1[N:37]([CH3:38])[C:36]([S:39][CH3:40])=[N:35][CH:34]=1)#[CH:32]>>[C:16]([C:14]1[CH:13]=[C:12]([NH:20][S:21]([CH3:24])(=[O:22])=[O:23])[C:11]([O:25][CH3:26])=[C:10]([NH:9][C:7](=[O:8])[C:6]2[CH:27]=[CH:28][C:29]([CH3:30])=[C:4]([N:1]3[CH:32]=[C:31]([C:33]4[N:37]([CH3:38])[C:36]([S:39][CH3:40])=[N:35][CH:34]=4)[N:3]=[N:2]3)[CH:5]=2)[CH:15]=1)([CH3:18])([CH3:19])[CH3:17]