HRID1350709

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1c(NC(=O)c2ccc(C)c(N=[N+]=[N-])c2)cc(C2(C)CC2)cc1NS(C)(=O)=O

HCID21097299

未命名化合物

HCID21097345

未命名化合物

PRODUCTS

生成物

结构：COc1c(NC(=O)c2ccc(C)c(-n3cc(-c4cnc(C(=O)c5ccccc5)n4C)nn3)c2)cc(C2(C)CC2)cc1NS(C)(=O)=O

HCID21097074

未命名化合物

PROCEDURE

实验过程

Example 34 was prepared from (5-ethynyl-1-methyl-1H-imidazol-2-yl)-phenyl-methanone (Example 33) and 3-azido-N-[3-methanesulfonylamino-2-methoxy-5-(1-methyl-cyclopropyl)-phenyl]-4-methyl-benzamide (Example 33) in the same manner as Example 15. ESI MS m/z 640 [C33H33N7O5S+H]+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-607a66c77c4747e591d9f10cdad8315f
来源数据集: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07214802B2
来源说明: uspto-grants-2007_05

反应 SMILES

[C:1]([C:3]1[N:7]([CH3:8])[C:6]([C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:10])=[N:5][CH:4]=1)#[CH:2].[N:17]([C:20]1[CH:21]=[C:22]([CH:43]=[CH:44][C:45]=1[CH3:46])[C:23]([NH:25][C:26]1[CH:31]=[C:30]([C:32]2([CH3:35])[CH2:34][CH2:33]2)[CH:29]=[C:28]([NH:36][S:37]([CH3:40])(=[O:39])=[O:38])[C:27]=1[O:41][CH3:42])=[O:24])=[N+:18]=[N-:19]>>[C:9]([C:6]1[N:7]([CH3:8])[C:3]([C:1]2[N:19]=[N:18][N:17]([C:20]3[CH:21]=[C:22]([CH:43]=[CH:44][C:45]=3[CH3:46])[C:23]([NH:25][C:26]3[CH:31]=[C:30]([C:32]4([CH3:35])[CH2:33][CH2:34]4)[CH:29]=[C:28]([NH:36][S:37]([CH3:40])(=[O:39])=[O:38])[C:27]=3[O:41][CH3:42])=[O:24])[CH:2]=2)=[CH:4][N:5]=1)(=[O:10])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1