Isobutyramide → 1-Methyl-2-(propan-2-yl)-1H-imidazole-5-carbaldehyde

HRID 1350725Notes

Reaction equation

HRID 1350725 reaction equation
C(N)(=O)C(C)C.[CH:7]1([C:10]2[N:14]([CH3:15])[C:13]([CH:16]=[O:17])=[CH:12][N:11]=2)[CH2:9][CH2:8]1>>[CH:7]([C:10]1[N:14]([CH3:15])[C:13]([CH:16]=[O:17])=[CH:12][N:11]=1)([CH3:9])[CH3:8]

Participants

3

Reactant 2

HCID 68424IsobutyramideHCID 210972742-cyclopropyl-3-methyl-3H-imidazole-4-carbaldehyde

Product 1

HCID 179567831-Methyl-2-(propan-2-yl)-1H-imidazole-5-carbaldehyde

Procedure

2-Isopropyl-3-methyl-3H-imidazole-4-carbaldehyde was prepared from isobutyramide in the same manner as 2-cyclopropyl-3-methyl-3H-imidazole-4-carbaldehyde (Example 46).

Sources & evidence

ORD record
ord-031553afab9b4892ae01582e3a7fc841
Source dataset
uspto-grants-2007_05
Patent number
US07214802B2

Reaction notes

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