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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1350728Generated: October 25, 2026

Tert-Butylamine → 1-tert-butyl-1H-imidazole-5-carbaldehyde

https://huagongshe.com/reaction/1350728

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-ButylamineHCID 6385—
ReactantEthyl formimidate hydrochlorideHCID 12578842—
Reactant3-cyclopropyl-2-methyl-3H-imidazole-4-carbaldehydeHCID 21097307—
Product1-tert-butyl-1H-imidazole-5-carbaldehydeHCID 21097315—

Reaction Steps

3-tert-Butyl-3H-imidazole-4-carbaldehyde was prepared from ethyl formimidate hydrochloride (Aldrich) and tert-butylamine in the same manner as 3-cyclopropyl-2-methyl-3H-imidazole-4-carbaldehyde (Example 45).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07214802B2
Source datasetuspto-grants-2007_05
ORD IDord-42c04b9c65444215843e2d4230708b99
Source noteuspto-grants-2007_05