Ethanamine, 2,2,2-trifluoro- → HCID 21097272, compound

HRID 1350762Notes

Reaction equation

HRID 1350762 reaction equation
C1(C(N)=O)CC1.[F:7][C:8]([F:12])([F:11])[CH2:9][NH2:10].[CH:13]1([C:16]2N(C)[C:19]([CH:22]=[O:23])=[CH:18][N:17]=2)[CH2:15][CH2:14]1>>[CH:13]1([C:16]2[N:10]([CH2:9][C:8]([F:12])([F:11])[F:7])[C:19]([CH:22]=[O:23])=[CH:18][N:17]=2)[CH2:15][CH2:14]1

Participants

4

Reactant 3

HCID 9773Ethanamine, 2,2,2-trifluoro-HCID 80376CyclopropanecarboxamideHCID 210972742-cyclopropyl-3-methyl-3H-imidazole-4-carbaldehyde

Product 1

HCID 21097272HCID 21097272, compound

Procedure

2-Cyclopropyl-3-(2,2,2-trifluoro-ethyl)-3H-imidazole-4-carbaldehyde was prepared from cyclopropyl carboxamide and 2,2,2-trifluoroethylamine in the same manner as 2-cyclopropyl-3-methyl-3H-imidazole-4-carbaldehyde (Example 46).

Sources & evidence

ORD record
ord-0f690c78437642d6be0034520666febf
Source dataset
uspto-grants-2007_05
Patent number
US07214802B2

Reaction notes

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