5-tert-Butyl-o-anisidine → 3-Azido-N-(5-tert-butyl-2-methoxy-phenyl)-4-methyl-benzamide

HRID 1350781Notes

Reaction equation

HRID 1350781 reaction equation
N(C1C=C(C=CC=1C)C(O)=O)=[N+]=[N-].C(C1C=CC(OC)=C(N)C=1)(C)(C)C.[N:27]([C:30]1[CH:31]=[C:32]([CH:53]=[CH:54][C:55]=1[CH3:56])[C:33]([NH:35][C:36]1[CH:41]=[C:40]([C:42]([CH3:45])([CH3:44])[CH3:43])[CH:39]=[C:38](NS(C)(=O)=O)[C:37]=1[O:51][CH3:52])=[O:34])=[N+:28]=[N-:29]>>[N:27]([C:30]1[CH:31]=[C:32]([CH:53]=[CH:54][C:55]=1[CH3:56])[C:33]([NH:35][C:36]1[CH:41]=[C:40]([C:42]([CH3:45])([CH3:44])[CH3:43])[CH:39]=[CH:38][C:37]=1[O:51][CH3:52])=[O:34])=[N+:28]=[N-:29]

Participants

4

Reactant 3

HCID 41763185-tert-Butyl-o-anisidineHCID 179730913-Azido-4-methylbenzoic acidHCID 210792023-azido-N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-benzamide

Product 1

HCID 210973013-Azido-N-(5-tert-butyl-2-methoxy-phenyl)-4-methyl-benzamide

Procedure

3-Azido-N-(5-tert-butyl-2-methoxy-phenyl)-4-methyl-benzamide was prepared from 3-azido-4-methyl benzoic acid (U.S. Ser. No. 04/102,492) and 5-tert-butyl-2-methoxy-phenylamine in the same manner as 3-azido-N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-benzamide (Example 15).

Sources & evidence

ORD record
ord-4d3b17bda99642c2ae4590f13edc7634
Source dataset
uspto-grants-2007_05
Patent number
US07214802B2

Reaction notes

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