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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1350806Generated: October 30, 2026

N-(3-amino-5-tert-butyl-2-methoxy-phenyl)-methanesulfonamide → N-(5-tert-Butyl-3-methanesulfonylamino-2-methoxy-phenyl)-3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzamide

https://huagongshe.com/reaction/1350806

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(3-amino-5-tert-butyl-2-methoxy-phenyl)-methanesulfonamideHCID 10214710—
Reactant3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzoic acid methyl esterHCID 58861445—
ProductN-(5-tert-Butyl-3-methanesulfonylamino-2-methoxy-phenyl)-3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzamideHCID 21097165—

Reaction Steps

Example 158 was prepared from N-(3-amino-5-tert-butyl-2-methoxy-phenyl)-methanesulfonamide and 3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzoic acid methyl ester (Example 151) in the same manner as Example 151. ESI MS m/z 627 [C34H38N6O4S+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07214802B2
Source datasetuspto-grants-2007_05
ORD IDord-bed0ee92c1b140b0aeab8ee1fe4f4758
Source noteuspto-grants-2007_05