HRID1350807

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID22506980

未命名化合物

结构：CCc1c(-c2cn(-c3cc(C(=O)OC)ccc3C)cn2)cnn1-c1ccccc1

HCID58861445

未命名化合物

PRODUCTS

生成物

结构：CCc1c(-c2cn(-c3cc(C(=O)Nc4cc(C(F)(F)F)cc(NS(C)(=O)=O)c4OC)ccc3C)cn2)cnn1-c1ccccc1

HCID21097094

未命名化合物

PROCEDURE

实验过程

Example 159 was prepared from N-(3-amino-2-methoxy-5-trifluoromethyl-phenyl)-methanesulfonamide and 3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzoic acid methyl ester (Example 151) in the same manner as Example 151. ESI MS m/z 639 [C31H29F3N6O4S+H]+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a3b4daaa692b49d783e756006955b840
来源数据集: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07214802B2
来源说明: uspto-grants-2007_05

反应 SMILES

[NH2:1][C:2]1[C:3]([O:17][CH3:18])=[C:4]([NH:12][S:13]([CH3:16])(=[O:15])=[O:14])[CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.C[O:20][C:21](=O)[C:22]1[CH:27]=[CH:26][C:25]([CH3:28])=[C:24]([N:29]2[CH:33]=[C:32]([C:34]3[CH:35]=[N:36][N:37]([C:41]4[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=4)[C:38]=3[CH2:39][CH3:40])[N:31]=[CH:30]2)[CH:23]=1>>[CH2:39]([C:38]1[N:37]([C:41]2[CH:42]=[CH:43][CH:44]=[CH:45][CH:46]=2)[N:36]=[CH:35][C:34]=1[C:32]1[N:31]=[CH:30][N:29]([C:24]2[CH:23]=[C:22]([CH:27]=[CH:26][C:25]=2[CH3:28])[C:21]([NH:1][C:2]2[CH:7]=[C:6]([C:8]([F:9])([F:11])[F:10])[CH:5]=[C:4]([NH:12][S:13]([CH3:16])(=[O:15])=[O:14])[C:3]=2[O:17][CH3:18])=[O:20])[CH:33]=1)[CH3:40]