HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → tert-Butyl (4-tert-butyl-3-fluorophenoxy)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | tert-Butyl bromoacetate | HCID 79177 | — |
| Reactant | 4-Tert-butyl-3-fluorophenol | HCID 20583424 | — |
| Product | tert-Butyl (4-tert-butyl-3-fluorophenoxy)acetate | HCID 58640409 | 83.2% |
Reaction Steps
Sixty % sodium hydride (128 mg, 3.2 mmol), 4-tert-butyl-3-fluorophenol (450 mg, 2.7 mmol), tert-butyl bromoacetate (632 mg, 3.2 mmol) were treated in the same procedure described in Example 3(b) to furnish 634 mg (82% yield) of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07214824B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-58454812816f4f95a1c332263622964d |
| Source note | uspto-grants-2007_05 |