HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 58640416, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | tert-Butyl bromoacetate | HCID 79177 | — |
| Reactant | 5,5-DIMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-OL | HCID 20287702 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 58640416 | HCID 58640416 | 85.3% |
Reaction Steps
A mixture of 5,5-dimethyl-5,6,7,8-tetrahydronaphthalen-2-ol (2.0 g, 11.3 mmol), 60% sodium hydride (542 mg, 13.2 mmol), tert-butyl bromoacetate (3.3 g, 17 mmol) and tetrahydrofuran (THF) (10 ml) was treated in the same procedure described in Example 3(a) to furnish 2.8 g of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07214824B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-e45a36b684a04e32a319486166f23bda |
| Source note | uspto-grants-2007_05 |