Sodium Hydroxide → HCID 69516736, compound

Participants

Reaction Steps

To a solution of 4-(2-hydroxybenzyl)-1-(2-hydroxyethyl)-5-isopropyl-1,2-dihydropyrazol-3-one (90 mg), acetobromo-α-D-glucose (161 mg) and benzyl tri(n-butyl)ammonium chloride (101 mg) in dichloromethane (5 mL) was added 2 mol/L aqueous sodium hydroxide solution (0.81 mL), and the mixture was stirred at room temperature for 3 hours. The reaction mixture was purified by column chromatography on aminopropyl silica gel (eluent: ethyl acetate/hexane 1/1—ethyl acetate) to give the title compound (35 mg).

Provenance & Evidence