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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1351111Generated: October 27, 2026

1-(Bromomethyl)-3-chlorobenzene → 4-[2-(3-Chlorobenzyloxy)benzyl]-3-(beta-D-glucopyranosyloxy)-5-isopropyl-1H-pyrazole

https://huagongshe.com/reaction/1351111

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bromomethyl)-3-chlorobenzeneHCID 69838—
Reactant3-(beta-D-glucopyranosyloxy)-4-(2-hydroxybenzyl)-5-isopropyl-1H-pyrazoleHCID 69516549—
Product4-[2-(3-Chlorobenzyloxy)benzyl]-3-(beta-D-glucopyranosyloxy)-5-isopropyl-1H-pyrazoleHCID 10142686—

Reaction Steps

The title compound was prepared in a similar manner to that described in Example 11 using 3-(β-D-glucopyranosyloxy)-4-(2-hydroxybenzyl)-5-isopropyl-1H-pyrazole instead of 3-(β-D-glucopyranosyloxy)-4-(2-hydroxybenzyl)-1-(2-hydroxyethyl)-5-trifluoromethyl-1H-pyrazole and using 3-chlorobenzyl bromide instead of benzyl bromide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07217697B2
Source datasetuspto-grants-2007_05
ORD IDord-5f8d314da8ba46cdae95946bb1c4ed4d
Source noteuspto-grants-2007_05