Triethylamine → HCID 11197501, compound

Participants

Reaction Steps

To a solution of 7,8-dimethoxy-4-phenyl-5,6-dihydro-4H-1,3,4-triaza-phenalen-5-ol (91 mg, 0.28 mmol) (from Example 20, Step A, supra) and triethylamine (0.23 mL, 1.69 mmol) in dichloromethane (50 mL) at 0° C. was added methanesulfonyl chloride (0.087 mL, 1.12 mmol) (Aldrich). The reaction solution was the stirred at room temperature for 2 hours. The solution was then concentrated, the residue was purified by chromatography using EtOAc/CH2Cl2/NEt3 (1:4:0.05) as eluent to give the desired 7,8-dimethoxy-4-phenyl-4H-1,3,4-triaza-phenalene as a white solid. (Yield 47 mg, 55%).

Provenance & Evidence