2-Methyl-1-pentanol → 2-Methyl-1-pentyl 5-amino-4-oxopentanoate Hydrochloride

HRID 1351426Notes

Reaction equation

HRID 1351426 reaction equation
[CH3:1][CH:2]([CH2:5][CH2:6][CH3:7])[CH2:3][OH:4].[ClH:8].[NH2:9][CH2:10][C:11](=[O:17])[CH2:12][CH2:13][C:14](O)=[O:15]>>[ClH:8].[NH2:9][CH2:10][C:11](=[O:17])[CH2:12][CH2:13][C:14]([O:4][CH2:3][CH:2]([CH3:1])[CH2:5][CH2:6][CH3:7])=[O:15]

Participants

3

Reactant 2

HCID 77452-Methyl-1-pentanolHCID 123608Aminolevulinic Acid Hydrochloride

Product 1

HCID 574382512-Methyl-1-pentyl 5-amino-4-oxopentanoate Hydrochloride

Procedure

From 2-methyl-1-pentanol (6.0 ml) and 5-amino-4-oxopentanoic acid hydrochloride (1.0 g; 6.0 mmol) at 70° C. The reaction was complete after 3.5 h. The yield was 1.43 g (95%).

Workup

  1. customat 70° C

Sources & evidence

ORD record
ord-0499757234a946a4ab1e4f9d309fa883
Source dataset
uspto-grants-2007_05
Patent number
US07217736B2

Reaction notes

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