3-Fluorobenzylic alcohol → HCID 17989818, compound

HRID 1351442Notes

Reaction equation

HRID 1351442 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH2:5][OH:6].[ClH:10].[NH2:11][CH2:12][C:13](=[O:19])[CH2:14][CH2:15][C:16](O)=[O:17]>>[ClH:10].[NH2:11][CH2:12][C:13](=[O:19])[CH2:14][CH2:15][C:16]([O:6][CH2:5][C:4]1[CH:7]=[CH:8][CH:9]=[C:2]([F:1])[CH:3]=1)=[O:17]

Participants

3

Reactant 2

HCID 680083-Fluorobenzylic alcoholHCID 123608Aminolevulinic Acid Hydrochloride

Product 1

HCID 17989818HCID 17989818, compound

Procedure

From 3-fluorobenzyl alcohol (5.1 g; 40 mmol) and 5-amino-4-oxopentanoic acid hydrochloride (1.0 g; 6.0 mmol). The reaction was complete after 20 h at 100° C. The yield was 1.04 g (72%). Mp 115–119° C.

Sources & evidence

ORD record
ord-f30ef5c39b10490abd78f18a1e59db65
Source dataset
uspto-grants-2007_05
Patent number
US07217736B2

Reaction notes

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