HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 3,4,5-Trichloropyridazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 4,5-Dichloro-3-hydroxypyridazine | HCID 73247 | — |
| Product | 3,4,5-Trichloropyridazine | HCID 70111 | — |
Reaction Steps
A stirred solution of 4,5-dichloro-2,3-dihydro-3-pyridazinone (15.00 g, 90.92 mmol) in POCl3 (100 mL) was refluxed for 1.5 h, then concentrated in vacuo. The residue was dissolved in CH2Cl2 (400 mL), washed with water (100 mL), dried over Na2SO4, filtered and concentrated to give 3,4,5-trichloropyridazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07217716B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-287667a72d7a49b49de9b9738dc71f36 |
| Source note | uspto-grants-2007_05 |