2,5-Dioxopyrrolidin-1-yl (4-methylbenzyl) carbonate → Carbonic acid 4-cyclopropyl-benzyl ester 2,5-dioxo-pyrrolidin-1-yl ester

HRID 1351533Notes

Reaction equation

HRID 1351533 reaction equation
[CH:1]1([C:4]2[CH:9]=[CH:8][C:7]([CH2:10][OH:11])=[CH:6][CH:5]=2)[CH2:3][CH2:2]1.CC1C=CC(C[O:18][C:19](=O)[O:20][N:21]2[C:25](=[O:26])[CH2:24][CH2:23][C:22]2=[O:27])=CC=1>>[O:27]=[C:22]1[CH2:23][CH2:24][C:25](=[O:26])[N:21]1[O:20][C:19](=[O:18])[O:11][CH2:10][C:7]1[CH:6]=[CH:5][C:4]([CH:1]2[CH2:3][CH2:2]2)=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 111399512,5-Dioxopyrrolidin-1-yl (4-methylbenzyl) carbonateHCID 22135711(4-Cyclopropylphenyl)methanol

Product 1

HCID 23577252Carbonic acid 4-cyclopropyl-benzyl ester 2,5-dioxo-pyrrolidin-1-yl ester

Procedure

The title compound was prepared from (4-cyclopropyl-phenyl)-methanol as described for similar compounds previously (Chem. Pharm. Bull., 38(1):110–115(1990) and INTERMEDIATE 1A).

Sources & evidence

ORD record
ord-0d216786aef8412c9c69be7bb9aa1cbc
Source dataset
uspto-grants-2007_05
Patent number
US07217716B2

Reaction notes

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