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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1351555Generated: October 27, 2026

6-chloro-9-methyl-9H-purine → (9-Methyl-9H-purin-6-yl)-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-ylmethyl]-amine

https://huagongshe.com/reaction/1351555

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-chloro-9-methyl-9H-purineHCID 94844—
Reactant[1-(2-Phenylethylsulfonyl)piperidin-4-yl]methanamineHCID 22135729—
Product(9-Methyl-9H-purin-6-yl)-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-ylmethyl]-amineHCID 10136541—

Reaction Steps

EXAMPLE 84 was prepared from C-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-yl]-methylamine and 6-chloro-9-methyl-9H-purine (6-chloro-9-methyl-9H-purine prepared according to G. B. Eilon, J. Org. Chem., 27:2478–2491(1962):

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07217716B2
Source datasetuspto-grants-2007_05
ORD IDord-3abe819fcd4247729c92e4a08b7eb202
Source noteuspto-grants-2007_05