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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1351559Generated: November 3, 2026

2,3-Dichloropyrazine → (3-Chloro-pyrazin-2-yl)-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-ylmethyl]-amine

https://huagongshe.com/reaction/1351559

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-DichloropyrazineHCID 78575—
Reactant[1-(2-Phenylethylsulfonyl)piperidin-4-yl]methanamineHCID 22135729—
Product(3-Chloro-pyrazin-2-yl)-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-ylmethyl]-amineHCID 23577245—

Reaction Steps

EXAMPLE 89 was prepared from C-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-yl]-methylamine and 2,3-dichloropyrazine (refluxing 2-butanol):

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07217716B2
Source datasetuspto-grants-2007_05
ORD IDord-de1168e71e2d40009720b41d4c376c73
Source noteuspto-grants-2007_05